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The AWS Typology
A New Approach to the Diagnosis, Management and Treatment of Alcohol Withdrawal
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The Old Way
  • Alcohol Withdrawal is a single condition, ranging from mild to severe
  • Benzodiazepine monotherapy is the preferred treatment regardless of symptoms
  • Symptoms graded on a numerical scale, based on severity
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The AWS Typology - The New Way
  • Alcohol Withdrawal consists of three distinct symptom clusters
  • Drug treatment should be tailored to the symptoms present, using the agents that best treat those symptoms
  • Symptoms graded only for absence or presence, using the AWS Type Indicator
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Advantages of the AWS Typology
  • Tailoring drug treatment to specific symptoms results in a more alert and cooperative patient
  • Avoids dangers associated with over-medication
  • Quickly identifies symptoms associated with serious complications
  • Reduces complications, morbidity, and mortality
  • Easily tracks development of symptoms and responses to treatment
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The AWS Type Indicator
  • A simple binary scale (symptoms are either present or absent)
  • Requires minimal training
  • Can be administered in 90 seconds or less
  • Guides treatment decisions
  • Monitors response to treatment
  • Designed for clinical use, not as a research tool
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Type A AWS
(CNS Excitation)
  • Symptoms
  • Uneasiness
  • Sense of Foreboding
  • Motor Hyperactivity
  • Dysphoria
  • Enhanced Sensivity to Abrupt Sensory Stimuli
  • Lability of Mood
  • Anxiety
  • Insomnia
  • Preferred Agents
  • Benzodiazepines
  • Carbamazepine
  • Valproic Acid
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Type B AWS
(Adrenergic Hyperactivity)
  • Symptoms
  • Chills
  • Diaphoresis
  • Fever
  • Hypermetabolic State
  • Hypertension
  • Muscle Tremors
  • Mydriasis
  • Nausea and Vomiting
  • Palpitations
  • Piloerection
  • Tachycardia
  • Preferred Agents
  • Clonidine
  • Beta-Blockers
    • Propranolol
    • Atenolol
    • Labetalol
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Type C AWS
(Alcohol Withdrawal Delirium)
  • Symptoms
  • Attentional Deficit
  • Disorientation
  • Hyper-alertness
  • Impairment of Short-term Memory
  • Impaired Reasoning
  • Psyhomotor Agitation
  • Visual and Auditory Hallucinations
  • Preferred Agents
  • Neuroleptics
    • Haloperidol
    • Fluphenazine
    • Risperidone
    • Droperidol
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Types A, B, and C
(Delirium Tremens)
  • Symptoms
  • Combination of A, B, and C Symptoms
  • Preferred Agents
  • Control of Type A Symptoms, Avoiding Benzodiazepines
  • Control of Type B Symptoms with Clonidine or Beta-Blockers
  • Control of Type C Symptoms with Low-dose Neuroleptics
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Preferred Agents
  • Agent
  • Benzodiazepines
  • Carbamazepine
  • Valproic Acid
  • Clonidine
  • Beta-Blockers
  • Neuroleptics
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Disadvantages of Benzodiazepine Monotherapy
  • Benzodiazepines are not particularly effective at controlling hyperadrenergic symptoms, including hypertension (Type B AWS)
  • Can result in unwanted and prolonged sedation, especially in older patients
  • Can produce cognitive and memory impairments
  • Can worsen delirium (Type C AWS)
  • Can result in respiratory compromise
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Prioritizing AWS Symptoms
  • Treat lowest level symptoms first
    • A, then B, then C except in emergencies
  • Re-administer Type Indicator Frequently
  • Typical Emergencies
    • Severe Type B symptoms, such as severe hypertension, tachycardia
    • Severe Type C symptoms (alcohol withdrawal delirium) including agitation that poses a danger to patient or others
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For More Information
  • The Acohol Withdrawal Treatment Manual
    • provides extensive and detailed information on treatment, pharmacotherapy, and the AWS Typology
      • Available on Amazon.com
  • Focused Treatment Systems website
    • http://www.sagetalk.com/
      • includes free downloadable copies of Type Indicator, resources on other topics